Clarithromycin interaction with simvastatin
WebClarithromycin has the following interaction information: Drug interaction information Severe interactions are highlighted with a red marker. Find out more about BNF … WebApr 27, 2024 · An 81-year-old man developed rhabdomyolysis and drug-induced liver injury (DILI) following concomitant administration of simvastatin and clarithromycin. The man …
Clarithromycin interaction with simvastatin
Did you know?
WebJun 23, 2024 · confusion, spinning sensation; liver problems --loss of appetite, upper stomach pain, tiredness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or. kidney problems ... WebSee the list of drugs that interact with Colchicine. Includes information on severity of interaction and the level of evidence for it. ... Clarithromycin is predicted to increase the exposure to Colchicine. ... Simvastatin. Colchicine has been reported to cause rhabdomyolysis when given with Simvastatin. Manufacturer advises caution or monitor ...
WebApr 27, 2024 · An event is serious (based on the ICH definition) when the patient outcome is:Drug interaction. An 81-year-old man developed rhabdomyolysis and drug-induced liver injury (DILI) following concomitant administration of simvastatin and clarithromycin. The man was admitted to the ED due to asthenia, muscle weakness … WebNguyễn Thị Huế, Lê Thị Hoàng Hà và cộng sự Clarithromycin – Simvastatin, Ciclosporin – (2024). Hiệu quả bước đầu của phần mềm cảnh báo hỗ trợ kê đơn trong quản lý tương tác thuốc Simvastatin, Domperidon – Moxifloxacin nhưng bất lợi tại Khoa Khám Bệnh.
WebQuetiapine — concurrent use is contraindicated. If necessary, monitor for adverse effects. Sildenafil, tadalafil — dose reductions may be necessary. Statins — concurrent administration with clarithromycin increases their plasma levels and the risk of myopathy. Lovastatin, simvastatin — concurrent use is contraindicated. WebDiscussion: Clarithromycin is a potent inhibitor of CYP3A4, the major enzyme responsible for simvastatin metabolism. The concomitant administration of macrolide …
WebJan 1, 2024 · The use of Clarithromycin tablets with lomitapide, simvastatin, lovastatin, ergotamine, or dihydroergotamine is contraindicated [see Contraindications (4.5, 4.6) and Drug Interactions (7)]. Colchicine : Life-threatening and fatal drug interactions have been reported in patients treated with Clarithromycin tablets and colchicine.
WebFeb 5, 2024 · Certain drugs can interact with atorvastatin (Lipitor) and increase its side effects. These include fibrates, niacin supplements, cyclosporine, clarithromycin, itraconazole, HIV protease inhibitors, oral … eraserheads aloha milkywayWebIf clarithromycin is necessary, we recommend (a) avoiding co-administration with simvastatin, lovastatin or atorvastatin; (b) withholding or dose-reducing pitavastatin; (c) … findlay propertyWebJun 9, 2016 · If you're taking a statin and are 65 or older, steering clear of the antibiotics Biaxin (clarithromycin) and erythromycin can help keep you safe from some uncommon — but potentially life ... findlay pta to pt programWebApr 1, 2024 · Descriptions. Clarithromycin is used to treat bacterial infections in many different parts of the body. It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. This medicine is also used to prevent and treat Mycobacterium avium complex (MAC) infection. Clarithromycin belongs to the class of … eraserheads best hitsWebClarithromycin Interactions. There are 660 drugs known to interact with clarithromycin, along with 5 disease interactions, and 1 alcohol/food interaction.Of the total drug interactions, 235 are major, 378 are moderate, and 47 are minor. eraserheads biographyWebOct 19, 2024 · If clarithromycin is necessary, we recommend (a) avoiding co-administration with simvastatin, lovastatin or atorvastatin; (b) withholding or dose-reducing … findlay pta to dptWebDec 28, 2024 · Simvastatin reduces cholesterol, Very Low-Density Lipoproteins (VLDL), and triglycerides while increasing HDL-cholesterol. 7. Interactions. Medicines that interact with simvastatin may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with simvastatin. findlay psychiatrist