Erk2 molecular weight
WebMay 27, 2024 · The liver weight is similar between WT and Erk2−/−mice. However, the body weight in Erk2−/−mice is slightly lower than WT mice. Therefore, the percentages of liver weight to body weight in Erk2−/−mice were higher than those of WT mice (Figure 1b). The percentages of α-SMA in KO liver sections were similar to that in WT sections. WebUse a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa. IHC-P ... Wild-type and ERK2 (MAPK1) knockout samples were subjected to SDS-PAGE. ab231085 and ab181602 (Rabbit anti-GAPDH loading control) were incubated overnight at 4°C at a 1µg/ml concentration and 1/20000 dilution respectively.
Erk2 molecular weight
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WebMolecular function Cellular component: Biological process: Sources:Amigo / ... (MAPK 1), also known as ERK2, is an enzyme that in humans is encoded by the MAPK1 gene. ... Heart weight: Normal Tail epidermis … WebNov 19, 2024 · In each experiment, 5 µM WT-ERK2, ERK2 mutants, WT-JNK1/2, WT-p38MAPKα or ERK5 catalytic domain protein were incubated ±100 µM BI-78D3 in 25 mM HEPES buffer (pH 7.5) containing 50 mM KCl, 0.1 ...
WebBody weight: Normal Anxiety: Normal Neurological assessment: Normal Grip strength: Normal Hot plate: Normal Dysmorphology: Normal: Indirect calorimetry: Normal Glucose tolerance test: Normal Auditory brainstem … WebJun 23, 2024 · Extracellular signal-regulated kinase 1 (ERK1) and ERK2 relay cell growth and mitogenic signals to multiple substrates, and thus control essential physiological processes. This Review discusses ...
WebMolecular Biology • PCR & qPCR • RT-PCR ... ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC 50 of 0.3 nM against ERK2. HY-151634 Syk-IN-6. … WebDec 13, 2024 · ERK2 mini-fragment binding. We present a novel crystallographic screening methodology (MiniFrags) that employs high-concentration aqueous soaks with a chemically diverse and ultra-low-molecular-weight library (heavy atom count 5-7) to identify ligand-binding hot and warm spots on proteins.
WebMAPK1: A gene on chromosome 22q11.2 22q11.21 that encodes a protein of the MAP kinase family. MAP kinases (e.g., extracellular signal-regulated kinases) integrate …
WebHighly specific and rigorously validated in-house, p42 MAP Kinase (Erk2) Antibody (CST #9108) is ready to ship. ... Loading of prestained molecular weight markers (#59329, 10 µl/lane) to verify electrotransfer and … havertys online paystubWebKey features and details Rabbit polyclonal to ERK1 + ERK2 Suitable for: ICC, IHC-P, WB Reacts with: Mouse, Rat, Human Isotype: IgG Get better batch-to-batch reproducibility … borse ingrosso onlineWebPhospho-ERK1/ERK2 (Thr202, Tyr204) Antibody (36-8800) in ICC/IF Immunofluorescent analysis of Phospho-p44 MAPK + p42 MAPK pThr202 + pTyr204 Antibody was done on 70% confluent log phase A549 cells. havertys online wage statementWebFeb 28, 2024 · Specifically, a strong band of 2pERK was detected in mitochondria, which matches the molecular weight of ERK2, indicating a strong differential regulation of ERK2 in mitochondria. Then, H 2 O 2 administration promotes a strong appearance of pTyr signal in mitochondria, suggesting that the translocated pYERK now is double phosphorylated … borse inps master executiveWebNov 1, 2024 · ERK2 phosphorylates GLI1 on three evolutionarily conserved target sites (S102, S116, and S130) located near the high-affinity binding site for SUFU; these phosphorylations cooperate to weaken the affinity of GLI1–SUFU binding by over 25-fold. ... For all gels, lane 1 is molecular weight standards (Precision Plus; Bio-Rad … borse in tessutoWebVX-11e (VTX-11e, Vertex-11e) is a potent, selective, and orally bioavailable ERK2 inhibitor with Ki of <2 nM, over 200-fold selective over other kinases tested. CAS No. 896720-20-0 Selleck's VX-11e has been cited by 18 … borse interne moto bmwWebJan 15, 2024 · ERK1 and ERK2 are two important members of the MAPK/ERK pathway, with molecular weights of 44 and 42 kDa, respectively ( 33 ). The C-terminus of ERK5 contains a nuclear … havertys opened a credit card