The molecular evolution of spermatogenesis
WebNov 10, 2024 · During embryonic development in mammals, the testicles generally descend into the scrotum, making the testicular temperature 2–4 °C lower than the core … http://www.jgenetgenomics.org/article/doi/10.1016/j.jgg.2024.05.010
The molecular evolution of spermatogenesis
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WebDec 21, 2024 · Our study illuminates the molecular evolution of spermatogenesis and associated selective forces, and provides a resource for investigating the biology of the … WebNov 10, 2024 · During embryonic development in mammals, the testicles generally descend into the scrotum, making the testicular temperature 2–4 °C lower than the core temperature via heat exchange and clearance, and thus more beneficial for normal spermatogenesis.
WebNov 8, 2024 · Our analyses reveal that the rapid evolution of the testis is driven by accelerated fixation rates of gene expression changes, amino acid altering substitutions, … WebNov 10, 2024 · To explore the underlying molecular mechanism, we conducted comparative genomic analyses and functional assays on the spermatogenesis-related ubiquitin–proteasome system (UPS) genes essential to sperm formation in representative laurasiatherians. Here, positive selection and rapid evolution of spermatogenesis-related …
Web1 day ago · The authors also reconstructed the evolution of postzygotic mutations in different organs over the course of a life span and identified mutations with particularly deleterious impacts on human health. ... We hypothesized that the selection pressures on spermatogenesis, fertilization, and prenatal development may alter the types of mutations … WebOur study illuminates the molecular evolution of spermatogenesis and associated selective forces, and provides a resource for investigating the biology of the testis across …
WebJan 31, 2024 · Our findings advance understanding of gene evolution across spermatogenesis and underscore the fundamental importance of developmental context …
WebJan 31, 2024 · Genes involved in spermatogenesis tend to evolve rapidly, but we lack a clear understanding of how protein sequences and patterns of gene expression evolve across this complex developmental... most powerful outdoor tv antenna availableWebMay 27, 2010 · The evolutionary pressures associated with gene duplication and acquisition of testis function are discussed in the context of genome organization and transcriptional regulation. Post-meiotic differentiation of spermatids involves very dramatic changes in cell shape and acquisition of highly specialized features. most powerful outdoor tv antennaWebNov 8, 2024 · The rapid evolution of the testis was shown to be reflected at the molecular level based on bulk-tissue work 3-8 , but the molecular evolution of individual spermatogenic cell types across mammalian lineages remains largely uncharacterized. mini la newborn real boyWebSep 7, 2024 · Davis, M. P. et al. Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution. EMBO Rep. 18 , 1231–1247 (2024). most powerful outboard marine engineWebThe molecular evolution of spermatogenesis across mammals Kaessmann lab This Shiny app allows the interactive exploration of individual gene expression profiles of adult testis … most powerful outside tv antennaWebDec 21, 2024 · Main Text. Transposons can be powerful drivers of evolution. These mobile genetic elements have the remarkable capacity to introduce new coding or non-coding DNA into portions of the genome, modifying the expression or function of existing genes or generating completely novel genes [1].Given their repetitive sequence, they can also … minilang.readthedocs.ioWebMolecular Evolution across Mouse Spermatogenesis Abstract Genes involved in spermatogenesis tend to evolve rapidly, but we lack a clear understanding of how protein … most powerful over the air tv antenna